- Initial Population =
- AND: Age >= 18 year(s) at: "Measurement Period"
- AND: Age < 80 year(s) at: "Measurement Period"
- AND: Count >= 2 of: Union of:
- "Encounter, Performed: Office Visit"
- "Encounter, Performed: Patient Provider Interaction"
- during "Measurement Period"
- AND: $FirstDxColonCancerMP overlaps Occurrence A of $OVorF2FEncounter
- Denominator =
- AND: Intersection of:
- "Occurrence A of Procedure, Performed: Clinical Staging Procedure" satisfies all
- (result: Colon Distant Metastasis Status M0) starts before end of Occurrence A of $OVorF2FEncounter
- (result: Colon Distant Metastasis Status M0) starts after or concurrent with start of $FirstDxColonCancerMP
- Union of:
- Intersection of:
- "Procedure, Performed: Clinical Staging Procedure" satisfies any
- (result: Colon Cancer Primary Tumor Size T1)
- (result: Colon Cancer Primary Tumor Size T2)
- (result: Colon Cancer Primary Tumor Size T3)
- (result: Colon Cancer Primary Tumor Size T4a)
- (result: Colon Cancer Primary Tumor Size T4b)
- "Procedure, Performed: Clinical Staging Procedure" satisfies any
- (result: Colon Cancer Regional Lymph Node Status N1)
- (result: Colon Cancer Regional Lymph Node Status N1a)
- (result: Colon Cancer Regional Lymph Node Status N1b)
- (result: Colon Cancer Regional Lymph Node Status N1c)
- (result: Colon Cancer Regional Lymph Node Status N2a)
- (result: Colon Cancer Regional Lymph Node Status N2b)
- "Procedure, Performed: Clinical Staging Procedure" satisfies all
- (result: Colon Cancer Primary Tumor Size T4b)
- (result: Colon Cancer Regional Lymph Node Status N2)
- Denominator Exclusions =
- Numerator =
- AND:
- OR: "Medication, Administered: Chemotherapy for Colon Cancer - Capecitabine" satisfies all
- starts after start of "Occurrence A of Procedure, Performed: Clinical Staging Procedure (result)"
- starts before end of Occurrence A of $OVorF2FEncounter
- OR: "Medication, Order: Chemotherapy for Colon Cancer - Capecitabine" satisfies all
- starts after start of "Occurrence A of Procedure, Performed: Clinical Staging Procedure (result)"
- starts before end of Occurrence A of $OVorF2FEncounter
- OR:
- AND: "Medication, Administered: Chemotherapy for Colon Cancer - Fluorouracil" satisfies all
- starts after start of "Occurrence A of Procedure, Performed: Clinical Staging Procedure (result)"
- starts before end of Occurrence A of $OVorF2FEncounter
- AND: "Medication, Administered: Chemotherapy for Colon Cancer - Leucovorin and Levo-Leucovorin" satisfies all
- starts after start of "Occurrence A of Procedure, Performed: Clinical Staging Procedure (result)"
- starts before end of Occurrence A of $OVorF2FEncounter
- OR:
- AND: "Medication, Order: Chemotherapy for Colon Cancer - Fluorouracil" satisfies all
- starts after start of "Occurrence A of Procedure, Performed: Clinical Staging Procedure (result)"
- starts before end of Occurrence A of $OVorF2FEncounter
- AND: "Medication, Order: Chemotherapy for Colon Cancer - Leucovorin and Levo-Leucovorin" satisfies all
- starts after start of "Occurrence A of Procedure, Performed: Clinical Staging Procedure (result)"
- starts before end of Occurrence A of $OVorF2FEncounter
- OR:
- AND: "Medication, Order: Chemotherapy for Colon Cancer - Capecitabine" satisfies all
- starts after start of "Occurrence A of Procedure, Performed: Clinical Staging Procedure (result)"
- starts before end of Occurrence A of $OVorF2FEncounter
- AND: "Medication, Order: Chemotherapy for Colon Cancer - Oxaliplatin" satisfies all
- starts after start of "Occurrence A of Procedure, Performed: Clinical Staging Procedure (result)"
- starts before end of Occurrence A of $OVorF2FEncounter
- OR:
- AND: "Medication, Administered: Chemotherapy for Colon Cancer - Capecitabine" satisfies all
- starts after start of "Occurrence A of Procedure, Performed: Clinical Staging Procedure (result)"
- starts before end of Occurrence A of $OVorF2FEncounter
- AND: "Medication, Administered: Chemotherapy for Colon Cancer - Oxaliplatin" satisfies all
- starts after start of "Occurrence A of Procedure, Performed: Clinical Staging Procedure (result)"
- starts before end of Occurrence A of $OVorF2FEncounter
- OR:
- AND: "Medication, Administered: Chemotherapy for Colon Cancer - Fluorouracil" satisfies all
- starts after start of "Occurrence A of Procedure, Performed: Clinical Staging Procedure (result)"
- starts before end of Occurrence A of $OVorF2FEncounter
- AND: "Medication, Administered: Chemotherapy for Colon Cancer - Leucovorin and Levo-Leucovorin" satisfies all
- starts after start of "Occurrence A of Procedure, Performed: Clinical Staging Procedure (result)"
- starts before end of Occurrence A of $OVorF2FEncounter
- AND: "Medication, Administered: Chemotherapy for Colon Cancer - Oxaliplatin" satisfies all
- starts after start of "Occurrence A of Procedure, Performed: Clinical Staging Procedure (result)"
- starts before end of Occurrence A of $OVorF2FEncounter
- OR:
- AND: "Medication, Order: Chemotherapy for Colon Cancer - Fluorouracil" satisfies all
- starts after start of "Occurrence A of Procedure, Performed: Clinical Staging Procedure (result)"
- starts before end of Occurrence A of $OVorF2FEncounter
- AND: "Medication, Order: Chemotherapy for Colon Cancer - Leucovorin and Levo-Leucovorin" satisfies all
- starts after start of "Occurrence A of Procedure, Performed: Clinical Staging Procedure (result)"
- starts before end of Occurrence A of $OVorF2FEncounter
- AND: "Medication, Order: Chemotherapy for Colon Cancer - Oxaliplatin" satisfies all
- starts after start of "Occurrence A of Procedure, Performed: Clinical Staging Procedure (result)"
- starts before end of Occurrence A of $OVorF2FEncounter
- Numerator Exclusions =
- Denominator Exceptions =
- OR: $FirstDxColonCancerMP <= 120 day(s) starts before end of "Measurement Period"
- OR: Union of:
- "Diagnosis, Active: Metastatic Sites Common to Colon Cancer"
- "Diagnosis, Active: Allergy to Antineoplastic Therapy"
- "Diagnosis, Active: Intolerance to Antineoplastic Therapy"
- "Patient Characteristic: ECOG Performance Status-Poor"
- "Patient Characteristic Clinical Trial Participant: Clinical Trial Participant"
- "Medication, Intolerance: Chemotherapy for Colon Cancer - Capecitabine"
- "Medication, Allergy: Chemotherapy for Colon Cancer - Capecitabine Ingredient"
- "Medication, Intolerance: Chemotherapy for Colon Cancer - Fluorouracil"
- "Medication, Allergy: Chemotherapy for Colon Cancer - Fluorouracil Ingredient"
- "Medication, Intolerance: Chemotherapy for Colon Cancer - Leucovorin and Levo-Leucovorin"
- "Medication, Allergy: Chemotherapy for Colon Cancer - Leucovorin and Levo-Leucovorin Ingredient"
- "Medication, Intolerance: Chemotherapy for Colon Cancer - Oxaliplatin"
- "Medication, Allergy: Chemotherapy for Colon Cancer - Oxaliplatin Ingredient"
- overlaps Occurrence A of $OVorF2FEncounter
- OR:
- AND: Union of:
- "Medication, Administered not done: Medical Reason" for "Chemotherapy for Colon Cancer - Capecitabine"
- "Medication, Administered not done: Patient Reason" for "Chemotherapy for Colon Cancer - Capecitabine"
- "Medication, Administered not done: System Reason" for "Chemotherapy for Colon Cancer - Capecitabine"
- "Medication, Order not done: Medical Reason" for "Chemotherapy for Colon Cancer - Capecitabine Ingredient"
- "Medication, Order not done: Patient Reason" for "Chemotherapy for Colon Cancer - Capecitabine Ingredient"
- "Medication, Order not done: System Reason" for "Chemotherapy for Colon Cancer - Capecitabine Ingredient"
- starts during Occurrence A of $OVorF2FEncounter
- AND: Union of:
- "Medication, Administered not done: Medical Reason" for "Chemotherapy for Colon Cancer - Fluorouracil"
- "Medication, Administered not done: Patient Reason" for "Chemotherapy for Colon Cancer - Fluorouracil"
- "Medication, Administered not done: System Reason" for "Chemotherapy for Colon Cancer - Fluorouracil"
- "Medication, Order not done: Medical Reason" for "Chemotherapy for Colon Cancer - Fluorouracil Ingredient"
- "Medication, Order not done: Patient Reason" for "Chemotherapy for Colon Cancer - Fluorouracil Ingredient"
- "Medication, Order not done: System Reason" for "Chemotherapy for Colon Cancer - Fluorouracil Ingredient"
- starts during Occurrence A of $OVorF2FEncounter
- AND: Union of:
- "Medication, Administered not done: Medical Reason" for "Chemotherapy for Colon Cancer - Leucovorin and Levo-Leucovorin"
- "Medication, Administered not done: Patient Reason" for "Chemotherapy for Colon Cancer - Leucovorin and Levo-Leucovorin"
- "Medication, Administered not done: System Reason" for "Chemotherapy for Colon Cancer - Leucovorin and Levo-Leucovorin"
- "Medication, Order not done: Medical Reason" for "Chemotherapy for Colon Cancer - Leucovorin and Levo-Leucovorin Ingredient"
- "Medication, Order not done: Patient Reason" for "Chemotherapy for Colon Cancer - Leucovorin and Levo-Leucovorin Ingredient"
- "Medication, Order not done: System Reason" for "Chemotherapy for Colon Cancer - Leucovorin and Levo-Leucovorin Ingredient"
- starts during Occurrence A of $OVorF2FEncounter
- AND: Union of:
- "Medication, Administered not done: Medical Reason" for "Chemotherapy for Colon Cancer - Oxaliplatin"
- "Medication, Administered not done: Patient Reason" for "Chemotherapy for Colon Cancer - Oxaliplatin"
- "Medication, Administered not done: System Reason" for "Chemotherapy for Colon Cancer - Oxaliplatin"
- "Medication, Order not done: Medical Reason" for "Chemotherapy for Colon Cancer - Oxaliplatin Ingredient"
- "Medication, Order not done: Patient Reason" for "Chemotherapy for Colon Cancer - Oxaliplatin Ingredient"
- "Medication, Order not done: System Reason" for "Chemotherapy for Colon Cancer - Oxaliplatin Ingredient"
- starts during Occurrence A of $OVorF2FEncounter
- Stratification =
- $OVorF2FEncounter =
- Union of:
- "Encounter, Performed: Office Visit"
- "Encounter, Performed: Face-to-Face Interaction"
- during "Measurement Period"
- $FirstDxColonCancerMP =
- "Diagnosis, Active: Colon Cancer" satisfies all
- First:
- starts during "Measurement Period"
- "Diagnosis, Active: Allergy to Antineoplastic Therapy" using "Allergy to Antineoplastic Therapy Grouping Value Set (2.16.840.1.113883.3.526.3.1280)"
- "Diagnosis, Active: Colon Cancer" using "Colon Cancer Grouping Value Set (2.16.840.1.113883.3.526.3.391)"
- "Diagnosis, Active: Intolerance to Antineoplastic Therapy" using "Intolerance to Antineoplastic Therapy Grouping Value Set (2.16.840.1.113883.3.526.3.1287)"
- "Diagnosis, Active: Metastatic Sites Common to Colon Cancer" using "Metastatic Sites Common to Colon Cancer Grouping Value Set (2.16.840.1.113883.3.526.3.490)"
- "Encounter, Performed: Face-to-Face Interaction" using "Face-to-Face Interaction Grouping Value Set (2.16.840.1.113883.3.464.1003.101.12.1048)"
- "Encounter, Performed: Office Visit" using "Office Visit Grouping Value Set (2.16.840.1.113883.3.464.1003.101.12.1001)"
- "Encounter, Performed: Patient Provider Interaction" using "Patient Provider Interaction Grouping Value Set (2.16.840.1.113883.3.526.3.1012)"
- "Medication, Administered: Chemotherapy for Colon Cancer - Capecitabine" using "Chemotherapy for Colon Cancer - Capecitabine Grouping Value Set (2.16.840.1.113883.3.526.3.1288)"
- "Medication, Administered: Chemotherapy for Colon Cancer - Fluorouracil" using "Chemotherapy for Colon Cancer - Fluorouracil Grouping Value Set (2.16.840.1.113883.3.526.3.1289)"
- "Medication, Administered: Chemotherapy for Colon Cancer - Leucovorin and Levo-Leucovorin" using "Chemotherapy for Colon Cancer - Leucovorin and Levo-Leucovorin Grouping Value Set (2.16.840.1.113883.3.526.3.1290)"
- "Medication, Administered: Chemotherapy for Colon Cancer - Oxaliplatin" using "Chemotherapy for Colon Cancer - Oxaliplatin Grouping Value Set (2.16.840.1.113883.3.526.3.1291)"
- "Medication, Administered not done: Medical Reason" using "Medical Reason Grouping Value Set (2.16.840.1.113883.3.526.3.1007)"
- "Medication, Administered not done: Patient Reason" using "Patient Reason Grouping Value Set (2.16.840.1.113883.3.526.3.1008)"
- "Medication, Administered not done: System Reason" using "System Reason Grouping Value Set (2.16.840.1.113883.3.526.3.1009)"
- "Medication, Allergy: Chemotherapy for Colon Cancer - Capecitabine Ingredient" using "Chemotherapy for Colon Cancer - Capecitabine Ingredient Grouping Value Set (2.16.840.1.113883.3.526.3.1485)"
- "Medication, Allergy: Chemotherapy for Colon Cancer - Fluorouracil Ingredient" using "Chemotherapy for Colon Cancer - Fluorouracil Ingredient Grouping Value Set (2.16.840.1.113883.3.526.3.1486)"
- "Medication, Allergy: Chemotherapy for Colon Cancer - Leucovorin and Levo-Leucovorin Ingredient" using "Chemotherapy for Colon Cancer - Leucovorin and Levo-Leucovorin Ingredient Grouping Value Set (2.16.840.1.113883.3.526.3.1490)"
- "Medication, Allergy: Chemotherapy for Colon Cancer - Oxaliplatin Ingredient" using "Chemotherapy for Colon Cancer - Oxaliplatin Ingredient Grouping Value Set (2.16.840.1.113883.3.526.3.1495)"
- "Medication, Intolerance: Chemotherapy for Colon Cancer - Capecitabine" using "Chemotherapy for Colon Cancer - Capecitabine Grouping Value Set (2.16.840.1.113883.3.526.3.1288)"
- "Medication, Intolerance: Chemotherapy for Colon Cancer - Fluorouracil" using "Chemotherapy for Colon Cancer - Fluorouracil Grouping Value Set (2.16.840.1.113883.3.526.3.1289)"
- "Medication, Intolerance: Chemotherapy for Colon Cancer - Leucovorin and Levo-Leucovorin" using "Chemotherapy for Colon Cancer - Leucovorin and Levo-Leucovorin Grouping Value Set (2.16.840.1.113883.3.526.3.1290)"
- "Medication, Intolerance: Chemotherapy for Colon Cancer - Oxaliplatin" using "Chemotherapy for Colon Cancer - Oxaliplatin Grouping Value Set (2.16.840.1.113883.3.526.3.1291)"
- "Medication, Order: Chemotherapy for Colon Cancer - Capecitabine" using "Chemotherapy for Colon Cancer - Capecitabine Grouping Value Set (2.16.840.1.113883.3.526.3.1288)"
- "Medication, Order: Chemotherapy for Colon Cancer - Capecitabine Ingredient" using "Chemotherapy for Colon Cancer - Capecitabine Ingredient Grouping Value Set (2.16.840.1.113883.3.526.3.1485)"
- "Medication, Order: Chemotherapy for Colon Cancer - Fluorouracil" using "Chemotherapy for Colon Cancer - Fluorouracil Grouping Value Set (2.16.840.1.113883.3.526.3.1289)"
- "Medication, Order: Chemotherapy for Colon Cancer - Fluorouracil Ingredient" using "Chemotherapy for Colon Cancer - Fluorouracil Ingredient Grouping Value Set (2.16.840.1.113883.3.526.3.1486)"
- "Medication, Order: Chemotherapy for Colon Cancer - Leucovorin and Levo-Leucovorin" using "Chemotherapy for Colon Cancer - Leucovorin and Levo-Leucovorin Grouping Value Set (2.16.840.1.113883.3.526.3.1290)"
- "Medication, Order: Chemotherapy for Colon Cancer - Leucovorin and Levo-Leucovorin Ingredient" using "Chemotherapy for Colon Cancer - Leucovorin and Levo-Leucovorin Ingredient Grouping Value Set (2.16.840.1.113883.3.526.3.1490)"
- "Medication, Order: Chemotherapy for Colon Cancer - Oxaliplatin" using "Chemotherapy for Colon Cancer - Oxaliplatin Grouping Value Set (2.16.840.1.113883.3.526.3.1291)"
- "Medication, Order: Chemotherapy for Colon Cancer - Oxaliplatin Ingredient" using "Chemotherapy for Colon Cancer - Oxaliplatin Ingredient Grouping Value Set (2.16.840.1.113883.3.526.3.1495)"
- "Medication, Order not done: Medical Reason" using "Medical Reason Grouping Value Set (2.16.840.1.113883.3.526.3.1007)"
- "Medication, Order not done: Patient Reason" using "Patient Reason Grouping Value Set (2.16.840.1.113883.3.526.3.1008)"
- "Medication, Order not done: System Reason" using "System Reason Grouping Value Set (2.16.840.1.113883.3.526.3.1009)"
- "Patient Characteristic: ECOG Performance Status-Poor" using "ECOG Performance Status-Poor Grouping Value Set (2.16.840.1.113883.3.526.3.1279)"
- "Patient Characteristic Clinical Trial Participant: Clinical Trial Participant" using "Clinical Trial Participant Grouping Value Set (2.16.840.1.113883.3.526.3.1125)"
- "Procedure, Performed: Clinical Staging Procedure" using "Clinical Staging Procedure Grouping Value Set (2.16.840.1.113883.3.526.3.1098)"
- Attribute: "Result: Colon Distant Metastasis Status M0" using "Colon Distant Metastasis Status M0 Grouping Value Set (2.16.840.1.113883.3.526.3.1337)"
- Attribute: "Result: Colon Cancer Regional Lymph Node Status N1c" using "Colon Cancer Regional Lymph Node Status N1c Grouping Value Set (2.16.840.1.113883.3.526.3.1298)"
- Attribute: "Result: Colon Cancer Regional Lymph Node Status N2b" using "Colon Cancer Regional Lymph Node Status N2b Grouping Value Set (2.16.840.1.113883.3.526.3.1301)"
- Attribute: "Result: Colon Cancer Primary Tumor Size T4b" using "Colon Cancer Primary Tumor Size T4b Grouping Value Set (2.16.840.1.113883.3.526.3.1296)"
- Attribute: "Result: Colon Cancer Regional Lymph Node Status N2" using "Colon Cancer Regional Lymph Node Status N2 Grouping Value Set (2.16.840.1.113883.3.526.3.1299)"
- Attribute: "Result: Colon Cancer Primary Tumor Size T1" using "Colon Cancer Primary Tumor Size T1 Grouping Value Set (2.16.840.1.113883.3.526.3.1292)"
- Attribute: "Result: Colon Cancer Primary Tumor Size T4a" using "Colon Cancer Primary Tumor Size T4a Grouping Value Set (2.16.840.1.113883.3.526.3.1295)"
- Attribute: "Result: Colon Cancer Primary Tumor Size T2" using "Colon Cancer Primary Tumor Size T2 Grouping Value Set (2.16.840.1.113883.3.526.3.1293)"
- Attribute: "Result: Colon Cancer Regional Lymph Node Status N1a" using "Colon Cancer Regional Lymph Node Status N1a Grouping Value Set (2.16.840.1.113883.3.526.3.1327)"
- Attribute: "Result: Colon Cancer Primary Tumor Size T3" using "Colon Cancer Primary Tumor Size T3 Grouping Value Set (2.16.840.1.113883.3.526.3.1294)"
- Attribute: "Result: Colon Cancer Regional Lymph Node Status N1" using "Colon Cancer Regional Lymph Node Status N1 Grouping Value Set (2.16.840.1.113883.3.526.3.1297)"
- Attribute: "Result: Colon Cancer Regional Lymph Node Status N2a" using "Colon Cancer Regional Lymph Node Status N2a Grouping Value Set (2.16.840.1.113883.3.526.3.1300)"
- Attribute: "Result: Colon Cancer Regional Lymph Node Status N1b" using "Colon Cancer Regional Lymph Node Status N1b Grouping Value Set (2.16.840.1.113883.3.526.3.1328)"
- "Patient Characteristic Ethnicity: Ethnicity" using "Ethnicity CDCREC Value Set (2.16.840.1.114222.4.11.837)"
- "Patient Characteristic Payer: Payer" using "Payer SOP Value Set (2.16.840.1.114222.4.11.3591)"
- "Patient Characteristic Race: Race" using "Race CDCREC Value Set (2.16.840.1.114222.4.11.836)"
- "Patient Characteristic Sex: ONC Administrative Sex" using "ONC Administrative Sex AdministrativeGender Value Set (2.16.840.1.113762.1.4.1)"